Rabbit anti-Human SOD1 Polyclonal Antibody

The antibody against SOD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-154 of human SOD1 (NP_000445.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, IP, ELISA.

ADA-13042A

Number

Cat.No	ADA-13042A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SOD1
Target Synonyms	ALS; SOD; ALS1; IPOA; STAHP; hSod1; HEL-S-44; homodimer; SOD1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Rat brain, 293T, MCF7, Mouse brain, Mouse liver, Rat liver, Rat lung	Application	ELISA, WB, IF/ICC, IHC-P, IP

Cat.No

ADA-13042A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SOD1

Target Synonyms

ALS; SOD; ALS1; IPOA; STAHP; hSod1; HEL-S-44; homodimer; SOD1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Rat brain, 293T, MCF7, Mouse brain, Mouse liver, Rat liver, Rat lung

Application

ELISA, WB, IF/ICC, IHC-P, IP

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 2-154 of human SOD1 (NP_000445.1).	Target Species	Human
Immunogen Sequence	ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ	Uniprot ID	P00441

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 2-154 of human SOD1 (NP_000445.1).

Target Species

Human

Immunogen Sequence

ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ

Uniprot ID

P00441

Background Information

Uniprot Id

P00441
Target Species

Human
Target Name

SOD1
Target Full Name

Superoxide dismutase [Cu-Zn]
Target Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Target Involvement

Amyotrophic lateral sclerosis 1 (ALS1)
Target Subcellular Location

Cytoplasm. Mitochondrion. Nucleus.
Target Protein Families

Cu-Zn superoxide dismutase family
Target Research Area

Metabolism
Target Synonyms

ALS; ALS1; Amyotrophic lateral sclerosis 1 adult; Cu/Zn SOD; Cu/Zn superoxide dismutase; Epididymis secretory protein Li 44; HEL S 44; Homodimer; hSod1; Indophenoloxidase A; IPOA; Mn superoxide dismutase; SOD; SOD soluble; SOD1; SOD2; SODC; SODC_HUMAN; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; Superoxide dismutase 1 soluble; Superoxide dismutase Cu Zn; Superoxide dismutase cystolic
Target Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Rabbit anti-Human SOD1 Polyclonal Antibody

Specifications

Immunogen Information

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