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The antibody against SPZ1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-430 of human SPZ1 (NP_115956.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SPZ1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-430 of human SPZ1 (NP_115956.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07100A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPZ1 |
| Target Synonyms | CILD38; NYD-TSP1; PPP1R148; SPZ1 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | DU145 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-430 of human SPZ1 (NP_115956.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BXG8 | Immunogen Sequence |
Uniprot Id
Q9BXG8
Target Species
Human
Target Name
SPZ1
Target Full Name
Spermatogenic leucine zipper protein 1
Target Function
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
Target Synonyms
SPZ1; TSP1; Spermatogenic leucine zipper protein 1; Testis-specific protein 1; Testis-specific protein NYD-TSP1
Target Background
This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments.
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