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The antibody against SYCE1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SYCE1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02622A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SYCE1 |
| Target Synonyms | CT76; POF12; SPGF15; C10orf94; SYCE1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat kidney, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N0S2 | Immunogen Sequence |
Uniprot Id
Q8N0S2
Target Species
Human
Target Name
SYCE1
Target Full Name
Synaptonemal complex central element protein 1
Target Function
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination.
Target Involvement
Premature ovarian failure 12 (POF12); Spermatogenic failure, 15 (SPGF15)
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
SYCE family
Target Synonyms
SYCE1; C10orf94; Synaptonemal complex central element protein 1; Cancer/testis antigen 76; CT76
Target Background
This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants.
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