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Rabbit anti-Human TNS4 Polyclonal Antibody

The antibody against TNS4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 380-520 of human TNS4 (NP_116254.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01118A

The antibody against TNS4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 380-520 of human TNS4 (NP_116254.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01118A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTNS4
Target SynonymsCTEN; PP14434; TNS4FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples22Rv1, HepG2, MCF7, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 380-520 of human TNS4 (NP_116254.4).Target SpeciesHuman
Immunogen SequenceCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVUniprot IDQ8IZW8
Background Information
  • Uniprot Id

    Q8IZW8

  • Target Species

    Human

  • Target Name

    TNS4

  • Target Full Name

    Tensin-4

  • Target Function

    May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. May promote apoptosis, via its cleavage by caspase-3.

  • Target Subcellular Location

    Cell junction, focal adhesion. Cytoplasm, cytoskeleton.

  • Target Tissue Specificity

    Prostate and placenta. Down regulated in prostate cancer.

  • Target Synonyms

    C terminal tensin like; C terminal tensin like protein; C-terminal tensin-like protein; CTEN; FLJ14950; PP14434; TENS4_HUMAN; Tensin 4; Tensin-4; Tns4

  • Target Background

    Predicted to enable actin binding activity. Involved in protein localization. Located in focal adhesion.

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