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Rabbit anti-Human TPPP3 Polyclonal Antibody

The antibody against TPPP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-176 of human TPPP3 (NP_057048.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09428A

The antibody against TPPP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-176 of human TPPP3 (NP_057048.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09428A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTPPP3
Target Synonymsp20; CGI-38; TPPP/p20; p25gamma; TPPP3FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, HT-29, Mouse spinal cord, Rat lungApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-176 of human TPPP3 (NP_057048.2).Target SpeciesHuman
Immunogen SequenceMAASTDMAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKSKEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVKKUniprot IDQ9BW30
Background Information
  • Uniprot Id

    Q9BW30

  • Target Species

    Human

  • Target Name

    TPPP3

  • Target Full Name

    Tubulin polymerization-promoting protein family member 3

  • Target Function

    Regulator of microtubule dynamic that has microtubule bundling activity. Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton.

  • Target Protein Families

    TPPP family

  • Target Tissue Specificity

    Expressed in endometrium during the mid-secretory phase (LH + 7) (at protein level).

  • Target Synonyms

    CGI-38; p20; p25gamma; TPPP/p20; Tppp3; TPPP3_HUMAN; Tubulin polymerization-promoting protein family member 3

  • Target Background

    Enables tubulin binding activity. Involved in decidualization and microtubule bundle formation. Colocalizes with microtubule bundle and perinuclear region of cytoplasm.

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