Rabbit anti-Human TRPC1 Polyclonal Antibody

The antibody against TRPC1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPC1 (NP_001238774.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-02517A

Number

Cat.No	ADA-02517A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TRPC1
Target Synonyms	TRP1; HTRP-1; TRPC1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, MCF7, SKOV3, SW480	Application	ELISA, WB, IHC-P

Cat.No

ADA-02517A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TRPC1

Target Synonyms

TRP1; HTRP-1; TRPC1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, MCF7, SKOV3, SW480

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPC1 (NP_001238774.1).	Target Species	Human
Immunogen Sequence	LLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEG	Uniprot ID	P48995

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPC1 (NP_001238774.1).

Target Species

Human

Immunogen Sequence

LLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEG

Uniprot ID

P48995

Background Information

Uniprot Id

P48995
Target Species

Human
Target Name

TRPC1
Target Full Name

Short transient receptor potential channel 1
Target Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC1 sub-subfamily
Target Tissue Specificity

Seems to be ubiquitous.
Target Synonyms

HTRP 1; HTRP1; MGC133334; MGC133335; Mtrp1; Short transient receptor potential channel 1; Transient receptor potential canonical 1; Transient receptor potential cation channel subfamily C member 1; Transient receptor potential channel 1; Transient receptor protein 1; TRP 1; TRP 1 protein; Trp related protein 1; TRP-1; TRP1; TRP1 protein; TrpC1; Trpc1 transient receptor potential cation channel subfamily C member 1; TRPC1_HUMAN; Trrp1
Target Background

The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human TRPC1 Polyclonal Antibody

Specifications

Immunogen Information

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