Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against TTC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC5 (NP_612385.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TTC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC5 (NP_612385.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03537A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TTC5 |
| Target Synonyms | Strap; NEDCAFD; TTC5 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, A-431, MCF7, Mouse spleen, Mouse testis, Mouse thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC5 (NP_612385.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N0Z6 | Immunogen Sequence |
Uniprot Id
Q8N0Z6
Target Species
Human
Target Name
TTC5
Target Full Name
Tetratricopeptide repeat protein 5
Target Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Synonyms
TTC5Tetratricopeptide repeat protein 5; TPR repeat protein 5; Stress-responsive activator of p300; Strap
Target Background
Predicted to enable DNA binding activity and chromatin binding activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
