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The antibody against VAMP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human VAMP1 (NP_954740.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against VAMP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human VAMP1 (NP_954740.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-01086A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VAMP1 |
| Target Synonyms | SAX1; SYB1; CMS25; SPAX1; VAMP-1; VAMP1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human VAMP1 (NP_954740.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCK | Uniprot ID | P23763 |
Uniprot Id
P23763
Target Species
Human
Target Name
VAMP1
Target Full Name
Vesicle-associated membrane protein 1
Target Function
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
Target Involvement
Spastic ataxia 1, autosomal dominant (SPAX1)
Target Subcellular Location
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 2]: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein.
Target Protein Families
Synaptobrevin family
Target Tissue Specificity
Nervous system, skeletal muscle and adipose tissue.
Target Synonyms
VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1
Target Background
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
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