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The antibody against ZC3H14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human ZC3H14 (NP_997545.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ZC3H14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human ZC3H14 (NP_997545.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01453A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZC3H14 |
| Target Synonyms | SUT2; MRT56; UKp68; MSUT-2; NY-REN-37; ZC3H14 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-549, HT-1080, MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human ZC3H14 (NP_997545.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6PJT7 | Immunogen Sequence |
Uniprot Id
Q6PJT7
Target Species
Human
Target Name
ZC3H14
Target Full Name
Zinc finger CCCH domain-containing protein 14
Target Function
Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
Target Involvement
Mental retardation, autosomal recessive 56 (MRT56)
Target Subcellular Location
Nucleus speckle.; [Isoform 1]: Nucleus speckle.; [Isoform 3]: Nucleus speckle.; [Isoform 6]: Cytoplasm.
Target Protein Families
ZC3H14 family
Target Tissue Specificity
Isoform 1 and isoform 6 are expressed in fetal and adult brain. Isoform 1 and isoform 6 are expressed in fetal and adult temporal lobe.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
FLJ11806; Mammalian suppressor of tau pathology-2; MGC26892; MSUT-2; Nuclear protein UKp68; NY REN 37; NYREN 37; Renal carcinoma antigen NY REN 37; Renal carcinoma antigen NY-REN-37; Renal carcinoma antigen NYREN 37; suppressor of tau 2, C. elegans, homolog of; SUT2; UKp68; ZC3H14; ZC3HE_HUMAN; Zinc finger CCCH domain-containing protein 14; Zinc finger CCCH type containing 14
Target Background
The protein encoded by this gene is a poly(A)-binding protein that can affect gene expression and poly(A) tail length. The encoded protein may influence mRNA stability, nuclear export, and translation.
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