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The antibody against ZNF408 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 471-720 of human ZNF408 (NP_079017.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ZNF408 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 471-720 of human ZNF408 (NP_079017.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01224A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZNF408 |
| Target Synonyms | EVR6; RP72; ZNF408 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-549, HepG2, MCF7, Mouse liver, Mouse spleen, Mouse thymus, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 471-720 of human ZNF408 (NP_079017.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H9D4 | Immunogen Sequence |
Uniprot Id
Q9H9D4
Target Species
Human
Target Name
ZNF408
Target Full Name
Zinc finger protein 408
Target Function
May be involved in transcriptional regulation.
Target Involvement
Vitreoretinopathy, exudative 6 (EVR6); Retinitis pigmentosa 72 (RP72)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highest expression is observed in adult retina; abundantly expressed in the fetal eye. In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at
Target Synonyms
EVR6; PFM14; PR domain zinc finger protein 17; PRDM17; RP72; Zinc finger protein 408; ZN408_HUMAN; ZNF408
Target Background
The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP).
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