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The recombinant antibody against GATA3 was produced using a synthesized peptide derived from Human Phospho-GATA3 (S308) as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.
The recombinant antibody against GATA3 was produced using a synthesized peptide derived from Human Phospho-GATA3 (S308) as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.
$350.00
| Cat.No | ADC-56303A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | GATA3 | Form | Liquid |
| Species Reactivity | Human | Isotype | Rabbit IgG |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human Phospho-GATA3 (S308) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23771 |
Uniprot Id
P23771
Target Species
Human
Target Name
GATA3
Target Full Name
Trans-acting T-cell-specific transcription factor GATA-3
Target Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression.
Target Involvement
Hypoparathyroidism, sensorineural deafness, and renal disease (HDR)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
T-cells and endothelial cells.
Target Synonyms
GATA 3; GATA binding factor 3; GATA binding protein 3; GATA-binding factor 3; Gata3; GATA3_HUMAN; HDR; HDRS; MGC2346; MGC5199; MGC5445; Trans acting T cell specific transcription factor GATA 3; Trans-acting T-cell-specific transcription factor GATA-3
Target Background
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
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