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The antibody against Omega-hexatoxin-Hv1a was raised in rabbit using the Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.
The antibody against Omega-hexatoxin-Hv1a was raised in rabbit using the Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.
$299.00
Western Blot | Positive WB detected in Recombinant protein | All lanes: Omega-hexatoxin-Hv1a antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 25 kDa | Observed band size: 25 kDa
| Cat.No | ADC-55286A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Omega-hexatoxin-Hv1a |
| Target Synonyms | Omega-hexatoxin-Hv1a (Omega-HXTX-Hv1a) (Omega-atracotoxin-Hv1a) (AcTx-Hv1) (Omega-AcTx-Hv1a) | Form | Liquid |
| Species Reactivity | Hadronyche versuta | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa ) | Target Species | Hadronyche versuta (Blue mountains funnel-web spider) (Atrax versutus) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P56207 |
Uniprot Id
P56207
Target Species
Hadronyche versuta
Target Function
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons. Lethal to many insect species but not toxic to mammals. May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
Target Subcellular Location
Secreted.
Target Protein Families
Shiva superfamily, Omega toxin family
Target Tissue Specificity
Expressed by the venom gland.
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