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The antibody against sfl was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) NDST protein (1-172aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.
The antibody against sfl was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) NDST protein (1-172aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.
$299.00
Western Blot | Positive WB detected in Recombinant protein | All lanes: sfl antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 33.1 kDa | Observed band size: 34 kDa
| Cat.No | ADC-55405A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | sfl |
| Form | Liquid | Species Reactivity | Drosophila melanogaster (Fruit fly) |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Drosophila melanogaster (Fruit fly) NDST protein (1-172aa) | Target Species | Drosophila melanogaster (Fruit fly) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9V3L1 |
Uniprot Id
Q9V3L1
Target Species
Drosophila melanogaster
Target Name
SFL
Target Function
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in diffusion of morphogen wingless (wg) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of wg morphogens. Required for wg signaling during both embryonic and imaginal disk development. Also required for FGF receptor signaling.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Sulfotransferase 1 family, NDST subfamily
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