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Explore the potential of our Recombinant Human YWHAH protein, a critical component in signal transduction research. This protein is a partial variant of the 14-3-3 protein eta (Protein AS1) and is derived from the 4-246aa expression region of the human YWHAH gene. Sourced from E.coli, the protein comes with an N-terminal GST tag to facilitate purification and detection. Presented as a lyophilized powder, this Recombinant Human YWHAH protein boasts a purity of greater than 90% as determined by SDS-PAGE, ensuring reliable performance in your research endeavors.
Explore the potential of our Recombinant Human YWHAH protein, a critical component in signal transduction research. This protein is a partial variant of the 14-3-3 protein eta (Protein AS1) and is derived from the 4-246aa expression region of the human YWHAH gene.
Sourced from E.coli, the protein comes with an N-terminal GST tag to facilitate purification and detection. Presented as a lyophilized powder, this Recombinant Human YWHAH protein boasts a purity of greater than 90% as determined by SDS-PAGE, ensuring reliable performance in your research endeavors.
| Cat.No | ACP02298 | Target Name | YWHAH |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 4-246aa | Mol Weight | 54.9kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q04917 |
|---|
Uniprot Id
Q04917
Target Species
Human
Target Name
YWHAH
Target Full Name
14-3-3 protein eta
Target Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Target Protein Families
14-3-3 family
Target Tissue Specificity
Expressed mainly in the brain and present in other tissues albeit at lower levels.
Target Research Area
Signal Transduction
Target Synonyms
14 3 3 protein eta; 14-3-3 eta; 14-3-3 protein eta; 1433F_HUMAN; Brain protein 14-3-3; eta isoform; HGNC:12853; Protein AS1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein 1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; eta isoform; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta; Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide; YWHA 1; YWHA1; Ywhah
Target Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
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