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| Cat.No | ACP11001 | Target Name | MRPL46 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H2W6 |
|---|
Uniprot Id
Q9H2W6
Target Species
Human
Target Name
MRPL46
Target Full Name
Large ribosomal subunit protein mL46
Target Subcellular Location
Mitochondrion.
Target Protein Families
Mitochondrion-specific ribosomal protein mL46 family
Target Synonyms
39S ribosomal protein L46; 39S ribosomal protein L46 mitochondrial; C15orf4; L46mt; LIECG 2; LIECG2; MGC22762; mitochondrial; Mitochondrial ribosomal protein L46; MRP L46; MRP-L46; MRPL 46; Mrpl46; P2ECSL; RM46_HUMAN
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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