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Recombinant Human 39S ribosomal protein L46, mitochondrial (MRPL46), Truncated

ACP11001

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11001 Target NameMRPL46
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9H2W6
Background Information
  • Uniprot Id

    Q9H2W6

  • Target Species

    Human

  • Target Name

    MRPL46

  • Target Full Name

    Large ribosomal subunit protein mL46

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Mitochondrion-specific ribosomal protein mL46 family

  • Target Synonyms

    39S ribosomal protein L46; 39S ribosomal protein L46 mitochondrial; C15orf4; L46mt; LIECG 2; LIECG2; MGC22762; mitochondrial; Mitochondrial ribosomal protein L46; MRP L46; MRP-L46; MRPL 46; Mrpl46; P2ECSL; RM46_HUMAN

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

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