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| Cat.No | ACP23815 | Target Name | HPD |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-393 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P32754 |
|---|
Uniprot Id
P32754
Target Species
Human
Target Name
HPD
Target Full Name
4-hydroxyphenylpyruvate dioxygenase
Target Function
Key enzyme in the degradation of tyrosine.
Target Involvement
Tyrosinemia 3 (TYRSN3); Hawkinsinuria (HAWK)
Target Protein Families
4HPPD family
Target Research Area
Metabolism
Target Synonyms
4 HPPD; 4 hydroxyphenylpyruvate dioxygenase; 4 hydroxyphenylpyruvic acid oxidase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3 ; glyoxalase domain containing 3; HPD; HPPD_HUMAN; HPPDase; PPD
Target Background
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
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