Recombinant Human 40S ribosomal protein S4, X isoform (RPS4X)

Uniprot Id

P62701

Target Species

Human

Target Name

RPS4X

Target Full Name

Small ribosomal subunit protein eS4, X isoform

Target Subcellular Location

Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Target Protein Families

Eukaryotic ribosomal protein eS4 family

Target Synonyms

40S ribosomal protein S4; CCG2; Cell cycle gene 2; DXS306; FLJ40595; ribosomal protein S4; X-linked; Ribosomal protein S4X isoform; RPS4; rps4x; RS4X_HUMAN; S4; SCAR; SCR10; Single copy abundant mRNA protein; Single-copy abundant mRNA; X isoform

Target Background

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.