Recombinant Human 60S ribosomal protein L26 (RPL26)

Uniprot Id

P61254

Target Species

Human

Target Name

RPL26

Target Full Name

Large ribosomal subunit protein uL24

Target Function

Component of the large ribosomal subunit.

Target Involvement

Diamond-Blackfan anemia 11 (DBA11)

Target Protein Families

Universal ribosomal protein uL24 family

Target Synonyms

PL26L1; 60S ribosomal protein L26; 60S ribosomal protein L26 like 1; DBA11; FLJ46904; L26; OTTHUMP00000135333; PTB associated splicing factor; Ribosomal protein L26 ; Ribosomal protein L26 homolog; Ribosomal protein L26 like 1; Ribosomal protein L26 pseudogene 1; RL26_HUMAN; rpl26; RPL26P1

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. Alternative splicing results in multiple transcript variants.