Recombinant Human 60S ribosomal protein L3 (RPL3), Truncated

Uniprot Id

P39023

Target Species

Human

Target Name

RPL3

Target Full Name

Large ribosomal subunit protein uL3

Target Function

The L3 protein is a component of the large subunit of cytoplasmic ribosomes.

Target Subcellular Location

Nucleus, nucleolus. Cytoplasm.

Target Protein Families

Universal ribosomal protein uL3 family

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; HIV1 TAR RNA binding protein B; MGC103388; MGC104284; MGC72934; Ribosomal protein L3; Ribosomal protein L3, isoform a; RL3_HUMAN; rpl3; TARBP B; TARBP-B

Target Background

Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.