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Recombinant Human Acid phosphatase-like protein 2 (ACPL2)

ACP13313

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13313 Target NamePXYLP1
Target SynonymsPXYLP1; ACPL2; HEL124; XYLP; UNQ370/PRO706; 2-phosphoxylose phosphatase 1; EC 3.1.3.-; Acid phosphatase-like protein 2; Xylosyl phosphatase; epididymis luminal protein 124FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range24-480
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TE99
Background Information
  • Uniprot Id

    Q8TE99

  • Target Species

    Human

  • Target Name

    PXYLP1

  • Target Full Name

    2-phosphoxylose phosphatase 1

  • Target Function

    Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Histidine acid phosphatase family

  • Target Tissue Specificity

    Widely expressed. Strongly expressed in spleen, fetal liver, moderately in placenta, pancreas, kidney, thymus and colon.

  • Target Synonyms

    PXYLP1; ACPL2; HEL124; XYLP; UNQ370/PRO706; 2-phosphoxylose phosphatase 1; EC 3.1.3.-; Acid phosphatase-like protein 2; Xylosyl phosphatase; epididymis luminal protein 124

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