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| Cat.No | ACP18596 | Target Name | ACSM1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 32-577 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q08AH1 |
|---|
Uniprot Id
Q08AH1
Target Species
Human
Target Name
ACSM1
Target Full Name
Acyl-coenzyme A synthetase ACSM1, mitochondrial
Target Function
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate. Also catalyzes the activation of lipoate to lipoyl-nucleoside monophosphate. Activates lipoate with GTP at a 1000-fold higher rate than with ATP and activates both (R)- and (S)-lipoate to the respective lipoyl-GMP, with a preference for (R)-lipoate.
Target Subcellular Location
Mitochondrion matrix. Mitochondrion.
Target Protein Families
ATP-dependent AMP-binding enzyme family
Target Synonyms
ACSM1; ACSM1_HUMAN; Acyl-CoA synthetase medium-chain family member 1; Acyl-coenzyme A synthetase ACSM1; BUCS1; Butyrate--CoA ligase 1; Butyryl-coenzyme A synthetase 1; LAE; Lipoate-activating enzyme; MACS1; Middle-chain acyl-CoA synthetase 1; mitochondrial
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