Recombinant Human Adhesion G-protein coupled receptor G6 (ADGRG6), Truncated

Cat.No	ACP06027	Target Name	ADGRG6
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP06027

Target Name

ADGRG6

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q86SQ4

Background Information

Uniprot Id

Q86SQ4
Target Species

Human
Target Name

ADGRG6
Target Full Name

Adhesion G-protein coupled receptor G6
Target Function

G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling. May act as a receptor for PRNP which may promote myelin homeostasis.
Target Involvement

Lethal congenital contracture syndrome 9 (LCCS9)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity

Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
Target Research Area

Others
Target Synonyms

adhesion G protein coupled receptor G6; APG1; Developmentally regulated G protein coupled receptor; Developmentally regulated G-protein-coupled receptor; dj287g14.2; DREG; G protein coupled receptor 126; G-protein coupled receptor 126; GP126_HUMAN; GPR126; HBV PreS1 transactivated protein 2; HBV PreS1-transactivated protein 2; LCCS9; OTTHUMP00000017320; OTTHUMP00000237093; OTTHUMP00000237094; OTTHUMP00000237115; PR126; Probable G protein coupled receptor 126 [Precursor]; Probable G protein coupled receptor 126; Probable G-protein coupled receptor 126 [Precursor]; Probable G-protein coupled receptor 126; PS1TP2; Vascular inducible G protein coupled receptor; Vascular inducible G protein-coupled receptor; VIGR
Target Background

This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene.

Recombinant Human Adhesion G-protein coupled receptor G6 (ADGRG6), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Adhesion G-protein coupled receptor G6 (ADGRG6), Truncated Now

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