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Recombinant Human ADP-ribosyl cyclase 2 (BST1)

ACP18542

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP18542	Target Name	BST1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	29-293	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q10588

Background Information

Uniprot Id

Q10588
Target Species

Human
Target Name

BST1
Target Full Name

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
Target Function

Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families

ADP-ribosyl cyclase family
Target Tissue Specificity

Widely expressed.
Target Synonyms

ADP ribosyl cyclase 2; ADP-ribosyl cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BST 1; BST-1; BST1; BST1_HUMAN; cADPr hydrolase 2; CD157; CD157 antigen; Cyclic ADP ribose hydrolase 2; Cyclic ADP-ribose hydrolase 2; NAD(+) nucleosidase; OTTHUMP00000217617
Target Background

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

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Recombinant Human ADP-ribosyl cyclase 2 (BST1)

Specifications

Immunogen Information

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