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| Cat.No | ACP12984 | Target Name | ST8SIA2 |
|---|---|---|---|
| Target Synonyms | 8-sialyltransferase 8B; EC 2.4.99.-; Sialyltransferase 8B; SIAT8-B; Sialyltransferase St8Sia II; ST8SiaII; Sialyltransferase X; STX, ST8SIA2; SIAT8B; STX; Alpha-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92186 |
|---|
Uniprot Id
Q92186
Target Species
Human
Target Name
ST8SIA2
Target Full Name
Alpha-2,8-sialyltransferase 8B
Target Function
May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 29 family
Target Tissue Specificity
Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
Target Synonyms
ST8SIA2; SIAT8B; STX; Alpha-2,8-sialyltransferase 8B; EC 2.4.99.-; Sialyltransferase 8B; SIAT8-B; Sialyltransferase St8Sia II; ST8SiaII; Sialyltransferase X; STX
Target Background
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.
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