Recombinant Human Anti-Muellerian hormone type-2 receptor (AMHR2), Truncated

Cat.No	ACP18315	Target Name	AMHR2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP18315

Target Name

AMHR2

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q16671

Background Information

Uniprot Id

Q16671
Target Species

Human
Target Name

AMHR2
Target Full Name

Anti-Muellerian hormone type-2 receptor
Target Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Target Involvement

Persistent Muellerian duct syndrome 2 (PMDS2)
Target Subcellular Location

Membrane; Single-pass type I membrane protein.
Target Protein Families

Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily
Target Synonyms

AMH type II receptor; AMHR; AMHR2; AMHR2_HUMAN; Anti Mullerian hormone receptor; type II; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; MGC141312; MIS type II receptor; MISR2; MISRII; MRII; Muellerian hormone type 2 receptor; Muellerian hormone type II receptor; Muellerian inhibiting substance type II receptor; Mullerian hormone receptor type II; Mullerian inhibiting substance type II receptor
Target Background

This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Recombinant Human Anti-Muellerian hormone type-2 receptor (AMHR2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Anti-Muellerian hormone type-2 receptor (AMHR2), Truncated Now

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