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| Cat.No | ACP11544 | Target Name | EPB41L4B |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H329 |
|---|
Uniprot Id
Q9H329
Target Species
Human
Target Name
EPB41L4B
Target Full Name
Band 4.1-like protein 4B
Target Function
Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells. Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing. May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation.
Target Subcellular Location
Cytoplasm. Cell junction, tight junction.
Target Tissue Specificity
Expressed at higher levels in acute wounds than chronic wounds with increased expression in healing wounds, especially at the leading wound edge. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in testis with lower levels in prostate
Target Synonyms
Band 4.1 like protein 4B; Band 4.1-like protein 4B; CG1; DKFZp761N1814; E41LB_HUMAN; EHM 2; Epb41l4b; Erythrocyte membrane protein band 4.1 like 4B; FERM containing protein; FERM containing protein CG1; FERM-containing protein CG1; FLJ21596; OTTHUMP00000021883; OTTHUMP00000021884; Protein EHM2
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