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Recombinant Human Band 4.1-like protein 4B (EPB41L4B), Truncated

ACP11544

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11544 Target NameEPB41L4B
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9H329
Background Information
  • Uniprot Id

    Q9H329

  • Target Species

    Human

  • Target Name

    EPB41L4B

  • Target Full Name

    Band 4.1-like protein 4B

  • Target Function

    Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells. Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing. May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation.

  • Target Subcellular Location

    Cytoplasm. Cell junction, tight junction.

  • Target Tissue Specificity

    Expressed at higher levels in acute wounds than chronic wounds with increased expression in healing wounds, especially at the leading wound edge. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in testis with lower levels in prostate

  • Target Synonyms

    Band 4.1 like protein 4B; Band 4.1-like protein 4B; CG1; DKFZp761N1814; E41LB_HUMAN; EHM 2; Epb41l4b; Erythrocyte membrane protein band 4.1 like 4B; FERM containing protein; FERM containing protein CG1; FERM-containing protein CG1; FLJ21596; OTTHUMP00000021883; OTTHUMP00000021884; Protein EHM2

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