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| Cat.No | ACP11795 | Target Name | BCL2L12 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-334 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HB09 |
|---|
Uniprot Id
Q9HB09
Target Species
Human
Target Name
BCL2L12
Target Full Name
Bcl-2-like protein 12
Target Synonyms
B2L12_HUMAN; BCL 2 like 12 (proline rich); BCL 2 like 12; BCL 2 like 12 isoform 1; Bcl 2 like 12 protein; Bcl 2 related proline rich protein; Bcl-2-like protein 12; Bcl-2-related proline-rich protein; BCL2 like 12 (proline rich); BCL2 like 12; BCL2 like 12 isoform 1; Bcl2 like 12 protein; Bcl2 related proline rich protein; Bcl2-L-12; BCL2L12; BPR; MGC120313; MGC120314; MGC120315
Target Background
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
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