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| Cat.No | ACP10856 | Target Name | BTBD7 |
|---|---|---|---|
| Target Synonyms | 5730507E09Rik; 8030448M07; BTB (POZ) domain containing 7; BTB domain containing 7; BTB/POZ domain-containing protein 7; BTBD7; BTBD7_HUMAN; E130118E17Rik; FUP1; KIAA1525; mKIAA1525 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P203 |
|---|
Uniprot Id
Q9P203
Target Species
Human
Target Name
BTBD7
Target Full Name
BTB/POZ domain-containing protein 7
Target Function
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression.
Target Subcellular Location
Nucleus.
Target Synonyms
5730507E09Rik; 8030448M07; BTB (POZ) domain containing 7; BTB domain containing 7; BTB/POZ domain-containing protein 7; BTBD7; BTBD7_HUMAN; E130118E17Rik; FUP1; KIAA1525; mKIAA1525
Target Background
Predicted to be involved in regulation of branching involved in salivary gland morphogenesis. Predicted to be located in nucleus.
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