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| Cat.No | ACP06405 | Target Name | CLGN |
|---|---|---|---|
| Target Synonyms | CLGN; Calmegin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14967 |
|---|
Uniprot Id
O14967
Target Species
Human
Target Name
CLGN
Target Full Name
Calmegin
Target Function
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Target Protein Families
Calreticulin family
Target Tissue Specificity
Detected in testis (at protein level). Detected in testis.
Target Synonyms
CLGN; Calmegin
Target Background
Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility.
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