Recombinant Human Calmodulin (CALM1)

Cat.No	ACP09187	Target Name	CAM, CAM1ANDName:CALM2Synonyms:CAM2, CAM3, CAMBANDName:CALM3Synonyms:CALML2, CAMC, CAMIII, Name:CALM1Synonyms:CALM
Target Synonyms	CALM1; CALM; CAM; CAM1Calmodulin-1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	2-149
Protein Length	Full Length of Mature Protein	Purity	Greater than 85% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP09187

Target Name

CAM, CAM1ANDName:CALM2Synonyms:CAM2, CAM3, CAMBANDName:CALM3Synonyms:CALML2, CAMC, CAMIII, Name:CALM1Synonyms:CALM

Target Synonyms

CALM1; CALM; CAM; CAM1Calmodulin-1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

2-149

Protein Length

Full Length of Mature Protein

Purity

Greater than 85% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P0DP23

Background Information

Uniprot Id

P0DP23
Target Species

Human
Target Name

CALM1
Target Full Name

Calmodulin-1
Target Function

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding. Acts as a sensor to modulate the endomplasmic reticulum contacts with other organelles mediated by VMP1:ATP2A2.; (Microbial infection) Required for Legionella pneumophila SidJ glutamylase activity.
Target Involvement

Ventricular tachycardia, catecholaminergic polymorphic, 4 (CPVT4); Long QT syndrome 14 (LQT14)
Target Subcellular Location

Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
Target Protein Families

Calmodulin family
Target Synonyms

CALM1; CALM; CAM; CAM1Calmodulin-1

Recombinant Human Calmodulin (CALM1)

Specifications

Immunogen Information

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