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Recombinant Human Cap-specific mRNA (nucleoside-2′-O-)-methyltransferase 2 (CMTR2), Truncated

ACP08080

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP08080 Target NameCMTR2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8IYT2
Background Information
  • Uniprot Id

    Q8IYT2

  • Target Species

    Human

  • Target Name

    CMTR2

  • Target Full Name

    Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2

  • Target Function

    S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Synonyms

    CMTR2; AFT; FTSJD1; Cap-specific mRNA; nucleoside-2'-O--methyltransferase 2; Cap methyltransferase 2; Cap2 2'O-ribose methyltransferase 2; HMTr2; MTr2; FtsJ methyltransferase domain-containing protein 1; Protein adrift homolog

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