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Amino acids 36-155 form the expressed segment for recombinant Human CEACAM4. This CEACAM4 protein is expected to have a theoretical molecular weight of 16.7 kDa. The CEACAM4 protein was expressed in e.coli. The N-terminal 6xHis tag was fused into the coding gene segment of CEACAM4, making it easier to detect and purify the CEACAM4 recombinant protein in the later stages of expression and purification.Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is mainly studied in the field of male reproductive health. CEACAM4 is a cell adhesion molecule found on the surface of sperm cells, and studies emphasize its significance in mediating interactions between sperm and other cells within the male reproductive system. Researchers are delving into the molecular mechanisms by which CEACAM4 contributes to sperm-egg binding and fertilization, aiming to unravel insights that could have implications for fertility treatments and male reproductive health. While the primary focus is on male reproductive biology, CEACAM4 might also have relevance in broader areas such as cell adhesion research and molecular biology.
Amino acids 36-155 form the expressed segment for recombinant Human CEACAM4. This CEACAM4 protein is expected to have a theoretical molecular weight of 16.7 kDa. The CEACAM4 protein was expressed in e.coli. The N-terminal 6xHis tag was fused into the coding gene segment of CEACAM4, making it easier to detect and purify the CEACAM4 recombinant protein in the later stages of expression and purification.Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is mainly studied in the field of male reproductive health. CEACAM4 is a cell adhesion molecule found on the surface of sperm cells, and studies emphasize its significance in mediating interactions between sperm and other cells within the male reproductive system. Researchers are delving into the molecular mechanisms by which CEACAM4 contributes to sperm-egg binding and fertilization, aiming to unravel insights that could have implications for fertility treatments and male reproductive health. While the primary focus is on male reproductive biology, CEACAM4 might also have relevance in broader areas such as cell adhesion research and molecular biology.
| Cat.No | ACP04676 | Target Name | CEACAM4 |
|---|---|---|---|
| Target Synonyms | CEACAM4; CGM7Carcinoembryonic antigen-related cell adhesion molecule 4; Carcinoembryonic antigen CGM7; Non-specific cross-reacting antigen W236 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 36-155aa |
| Mol Weight | 16.7kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75871 |
|---|
Uniprot Id
O75871
Target Species
Human
Target Name
CEACAM4
Target Full Name
Cell adhesion molecule CEACAM4
Target Function
Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, CEA family
Target Tissue Specificity
Granulocytes.
Target Research Area
Immunology
Target Synonyms
CEACAM4; CGM7Carcinoembryonic antigen-related cell adhesion molecule 4; Carcinoembryonic antigen CGM7; Non-specific cross-reacting antigen W236
Target Background
Involved in phagocytosis. Predicted to be located in extracellular region.
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