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Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4), Truncated

Amino acids 36-155 form the expressed segment for recombinant Human CEACAM4. This CEACAM4 protein is expected to have a theoretical molecular weight of 16.7 kDa. The CEACAM4 protein was expressed in e.coli. The N-terminal 6xHis tag was fused into the coding gene segment of CEACAM4, making it easier to detect and purify the CEACAM4 recombinant protein in the later stages of expression and purification.Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is mainly studied in the field of male reproductive health. CEACAM4 is a cell adhesion molecule found on the surface of sperm cells, and studies emphasize its significance in mediating interactions between sperm and other cells within the male reproductive system. Researchers are delving into the molecular mechanisms by which CEACAM4 contributes to sperm-egg binding and fertilization, aiming to unravel insights that could have implications for fertility treatments and male reproductive health. While the primary focus is on male reproductive biology, CEACAM4 might also have relevance in broader areas such as cell adhesion research and molecular biology.

ACP04676

Amino acids 36-155 form the expressed segment for recombinant Human CEACAM4. This CEACAM4 protein is expected to have a theoretical molecular weight of 16.7 kDa. The CEACAM4 protein was expressed in e.coli. The N-terminal 6xHis tag was fused into the coding gene segment of CEACAM4, making it easier to detect and purify the CEACAM4 recombinant protein in the later stages of expression and purification.Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is mainly studied in the field of male reproductive health. CEACAM4 is a cell adhesion molecule found on the surface of sperm cells, and studies emphasize its significance in mediating interactions between sperm and other cells within the male reproductive system. Researchers are delving into the molecular mechanisms by which CEACAM4 contributes to sperm-egg binding and fertilization, aiming to unravel insights that could have implications for fertility treatments and male reproductive health. While the primary focus is on male reproductive biology, CEACAM4 might also have relevance in broader areas such as cell adhesion research and molecular biology.

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Specifications


Cat.No ACP04676 Target NameCEACAM4
Target SynonymsCEACAM4; CGM7Carcinoembryonic antigen-related cell adhesion molecule 4; Carcinoembryonic antigen CGM7; Non-specific cross-reacting antigen W236FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range36-155aa
Mol Weight16.7kDaProtein LengthPartial
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75871
Background Information
  • Uniprot Id

    O75871

  • Target Species

    Human

  • Target Name

    CEACAM4

  • Target Full Name

    Cell adhesion molecule CEACAM4

  • Target Function

    Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Immunoglobulin superfamily, CEA family

  • Target Tissue Specificity

    Granulocytes.

  • Target Research Area

    Immunology

  • Target Synonyms

    CEACAM4; CGM7Carcinoembryonic antigen-related cell adhesion molecule 4; Carcinoembryonic antigen CGM7; Non-specific cross-reacting antigen W236

  • Target Background

    Involved in phagocytosis. Predicted to be located in extracellular region.

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