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| Cat.No | ACP17001 | Target Name | CARD17 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-110 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5XLA6 |
|---|
Uniprot Id
Q5XLA6
Target Species
Human
Target Name
CARD17P
Target Full Name
Putative caspase recruitment domain-containing protein 17P
Target Function
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Ubiquitous.
Target Research Area
Cell Biology
Target Synonyms
CAR17_HUMAN; CARD 17; CARD17; Caspase 1 inhibitor; Caspase recruitment domain containing protein 17; Caspase recruitment domain-containing protein 17; Caspase-1 inhibitor INCA; Caspase1 inhibitor; Inhibitory caspase recruitment domain (CARD) protein; Inhibitory caspase recruitment domain protein
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