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Recombinant Human CDC42 small effector protein 2 (CDC42SE2)

ACP10917

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Specifications

Cat.No	ACP10917	Target Name	CDC42SE2
Target Synonyms	CDC42SE2; SPEC2CDC42 small effector protein 2; Small effector of CDC42 protein 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-84
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NRR3

Background Information

Uniprot Id

Q9NRR3
Target Species

Human
Target Name

CDC42SE2
Target Full Name

CDC42 small effector protein 2
Target Function

Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Target Subcellular Location

Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
Target Protein Families

CDC42SE/SPEC family
Target Tissue Specificity

Widely expressed. Expressed at higher level in T-lymphocytes. Highly expressed in CCRF-CEM T-lymphocytes, Jurkat T-lymphocytes, and Raji B-lymphocytes compared (at protein level).
Target Synonyms

CDC42SE2; SPEC2CDC42 small effector protein 2; Small effector of CDC42 protein 2

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Recombinant Human CDC42 small effector protein 2 (CDC42SE2)

Specifications

Immunogen Information

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