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| Cat.No | ACP11163 | Target Name | CDKN2AIP |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-580 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NXV6 |
|---|
Uniprot Id
Q9NXV6
Target Species
Human
Target Name
CDKN2AIP
Target Full Name
CDKN2A-interacting protein
Target Function
Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
Target Subcellular Location
Nucleus, nucleoplasm.
Target Protein Families
CARF family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
Calcium response factor; CARF; CARF_HUMAN; CDKN2A interacting protein; CDKN2A-interacting protein; Cdkn2aip; collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF; FLJ20036
Target Background
The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene.
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