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Recombinant Human Centromere protein O (CENPO)

ACP19139

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19139 Target NameCENPO
Target SynonymsCENPO; ICEN36; MCM21RCentromere protein O; CENP-O; Interphase centromere complex protein 36FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-300
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BU64
Background Information
  • Uniprot Id

    Q9BU64

  • Target Species

    Human

  • Target Name

    CENPO

  • Target Full Name

    Centromere protein O

  • Target Function

    Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.

  • Target Subcellular Location

    Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.

  • Target Protein Families

    CENP-O/MCM21 family

  • Target Synonyms

    CENPO; ICEN36; MCM21RCentromere protein O; CENP-O; Interphase centromere complex protein 36

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