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| Cat.No | ACP05467 | Target Name | CLCNKB |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51801 |
|---|
Uniprot Id
P51801
Target Species
Human
Target Name
CLCNKB
Target Full Name
Chloride channel protein ClC-Kb
Target Function
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Target Involvement
Bartter syndrome 3 (BARTS3); Bartter syndrome 4B, neonatal, with sensorineural deafness (BARTS4B)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Chloride channel (TC 2.A.49) family, CLCNKB subfamily
Target Tissue Specificity
Expressed predominantly in the kidney.
Target Synonyms
Bartter syndrome type 3; Chloride channel Kb; Chloride channel kidney B; Chloride channel protein ClC-Kb; Chloride channel voltage sensitive Kb; ClC K2; ClC-K2; ClCK2; CLCKB; CLCKB_HUMAN; CLCNKB; hClC Kb; hClCKb; MGC24087; OTTHUMP00000011120; OTTHUMP00000011121; RP11 5P18.8
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