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Recombinant Human Chloride intracellular channel protein 3 (CLIC3), Truncated

ACP06686

Number
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Specifications


Cat.No ACP06686 Target NameCLIC3
Target SynonymsCLIC3; Chloride intracellular channel protein 3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO95833
Background Information
  • Uniprot Id

    O95833

  • Target Species

    Human

  • Target Name

    CLIC3

  • Target Full Name

    Chloride intracellular channel protein 3

  • Target Function

    Can insert into membranes and form chloride ion channels. May participate in cellular growth control.

  • Target Subcellular Location

    Nucleus. Membrane; Single-pass membrane protein. Cytoplasm.

  • Target Protein Families

    Chloride channel CLIC family

  • Target Tissue Specificity

    Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.

  • Target Synonyms

    CLIC3; Chloride intracellular channel protein 3

  • Target Background

    Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.

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