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| Cat.No | ACP17457 | Target Name | CCDC40 |
|---|---|---|---|
| Target Synonyms | CCD40_HUMAN; ccdc 40; CCDC40; Coiled coil domain containing 40; Coiled-coil domain-containing protein 40; FLJ20753; FLJ32021; KIAA1640 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q4G0X9 |
|---|
Uniprot Id
Q4G0X9
Target Species
Human
Target Name
CCDC40
Target Full Name
Coiled-coil domain-containing protein 40
Target Function
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.
Target Involvement
Ciliary dyskinesia, primary, 15 (CILD15)
Target Subcellular Location
Cytoplasm. Cell projection, cilium.
Target Protein Families
CCDC40 family
Target Synonyms
CCD40_HUMAN; ccdc 40; CCDC40; Coiled coil domain containing 40; Coiled-coil domain-containing protein 40; FLJ20753; FLJ32021; KIAA1640
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