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| Cat.No | ACP17077 | Target Name | C1QL3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 21-255 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VWW1 |
|---|
Uniprot Id
Q5VWW1
Target Species
Human
Target Name
C1QL3
Target Full Name
Complement C1q-like protein 3
Target Function
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney.
Target Synonyms
C1q and tumor necrosis factor-related protein 13; C1q/TNF-related protein 13; C1ql; C1QL3; C1QL3_HUMAN; C1QTNF13; Complement C1q-like protein 3; Complement component 1; q subcomponent-like 3; CTRP13; K100
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