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| Cat.No | ACP01793 | Target Name | C8A |
|---|---|---|---|
| Target Synonyms | Complement component 8 subunit alpha | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 31-584aa |
| Mol Weight | 65.8 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P07357 |
|---|
Uniprot Id
P07357
Target Species
Human
Target Name
C8A
Target Full Name
Complement component C8 alpha chain
Target Function
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.
Target Involvement
Complement component 8 deficiency, 1 (C8D1)
Target Subcellular Location
Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein. Inserts into the cell membrane of target cells.
Target Protein Families
Complement C6/C7/C8/C9 family
Target Research Area
Immunology
Target Synonyms
C8A; CO8A_HUMAN; Complement component 8 subunit alpha; Complement component 8, alpha polypeptide; Complement component C8 alpha chain
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