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Recombinant Human Complement receptor type 2 (CR2), Truncated

ACP24097

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Specifications

Cat.No	ACP24097	Target Name	CR2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P20023

Background Information

Uniprot Id

P20023
Target Species

Human
Target Name

CR2
Target Full Name

Complement receptor type 2
Target Function

Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU. Participates in B lymphocytes activation.; (Microbial infection) Acts as a receptor for Epstein-Barr virus.
Target Involvement

Systemic lupus erythematosus 9 (SLEB9); Immunodeficiency, common variable, 7 (CVID7)
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

Receptors of complement activation (RCA) family
Target Tissue Specificity

Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Target Synonyms

C3DR; CD 21; CD21; Complement C3d receptor 2; Complement C3d receptor; Complement component (3d/Epstein Barr virus) receptor 2; Complement receptor type 2; CR; Cr2; CR2_HUMAN; CVID7; EBV receptor; EBV-R; Epstein Barr virus receptor; Epstein-Barr virus receptor; EVBR; SLEB9
Target Background

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Recombinant Human Complement receptor type 2 (CR2), Truncated

Specifications

Immunogen Information

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