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The process of expressing the recombinant Human NR2F1 protein includes transfecting e.coli cells with a DNA expression vector carrying the gene for the desired protein (1-423aa). Subsequently, the cells are cultured to induce the expression of the intended protein. The protein is equipped with a N-terminal 6xHis tag. The recombinant Human NR2F1 protein is then collected and purified from the cell lysate through affinity purification, exhibiting a purity exceeding 90%, as verified by SDS-PAGE.
The process of expressing the recombinant Human NR2F1 protein includes transfecting e.coli cells with a DNA expression vector carrying the gene for the desired protein (1-423aa). Subsequently, the cells are cultured to induce the expression of the intended protein. The protein is equipped with a N-terminal 6xHis tag. The recombinant Human NR2F1 protein is then collected and purified from the cell lysate through affinity purification, exhibiting a purity exceeding 90%, as verified by SDS-PAGE.
| Cat.No | ACP01700 | Target Name | NR2F1 |
|---|---|---|---|
| Target Synonyms | (COUP-TF1)(COUP transcription factor I)(COUP-TF I)(Nuclear receptor subfamily 2 group F member 1)(V-erbA-related protein 3)(EAR-3) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-423aa |
| Mol Weight | 50.2 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P10589 |
|---|
Uniprot Id
P10589
Target Species
Human
Target Name
NR2F1
Target Full Name
COUP transcription factor 1
Target Function
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG.
Target Involvement
Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS)
Target Subcellular Location
Nucleus.
Target Protein Families
Nuclear hormone receptor family, NR2 subfamily
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Chicken ovalbumin upstream promoter 1; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; EAR-3; EAR3; ERBAL3; NR2F1; NR2F2; Nuclear receptor subfamily 2 group F member 1; SVP44; TCFCOUP1; TFCOUP1; Transcription factor COUP 1; V ERBA related protein EAR 3; V-erbA-related protein 3
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