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Enhance your cancer research capabilities with our premium Recombinant Human ATF3 protein. ATF3, or cyclic AMP-dependent transcription factor ATF-3, is a key player in cellular stress responses, regulating various biological processes such as apoptosis, cell survival, and inflammation. Its role in these processes makes it an essential target in cancer research. Our Recombinant Human ATF3 protein represents the full-length protein, including the 1-181aa expression region, and is meticulously produced in E.coli. The N-terminal 6xHis-tag allows for ease of purification and detection, ensuring an exceptional product for your experiments. With a purity greater than 85% as determined by SDS-PAGE, our Recombinant Human ATF3 provides a reliable foundation for your cancer research needs. Available in both liquid and lyophilized powder forms, this protein caters to diverse experimental requirements.
Enhance your cancer research capabilities with our premium Recombinant Human ATF3 protein. ATF3, or cyclic AMP-dependent transcription factor ATF-3, is a key player in cellular stress responses, regulating various biological processes such as apoptosis, cell survival, and inflammation. Its role in these processes makes it an essential target in cancer research.
Our Recombinant Human ATF3 protein represents the full-length protein, including the 1-181aa expression region, and is meticulously produced in E.coli. The N-terminal 6xHis-tag allows for ease of purification and detection, ensuring an exceptional product for your experiments. With a purity greater than 85% as determined by SDS-PAGE, our Recombinant Human ATF3 provides a reliable foundation for your cancer research needs. Available in both liquid and lyophilized powder forms, this protein caters to diverse experimental requirements.
| Cat.No | ACP02339 | Target Name | ATF3 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-181aa | Mol Weight | 26.1 kDa |
| Protein Length | Full length | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P18847 |
|---|
Uniprot Id
P18847
Target Species
Human
Target Name
ATF3
Target Full Name
Cyclic AMP-dependent transcription factor ATF-3
Target Function
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTActivates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Target Subcellular Location
Nucleus.
Target Protein Families
BZIP family, ATF subfamily
Target Research Area
Cancer
Target Synonyms
Activating transcription factor 3; ATF3; ATF3_HUMAN; ATF3deltaZip2; ATF3deltaZip2c; ATF3deltaZip3; cAMP dependent transcription factor ATF3; cAMP-dependent transcription factor ATF-3; Cyclic AMP dependent transcription factor ATF3; Cyclic AMP-dependent transcription factor ATF-3
Target Background
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
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