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| Cat.No | ACP14360 | Target Name | AGBL1 |
|---|---|---|---|
| Target Synonyms | AGBL1; CCP4; Cytosolic carboxypeptidase 4; EC 3.4.17.-; ATP/GTP-binding protein-like 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96MI9 |
|---|
Uniprot Id
Q96MI9
Target Species
Human
Target Name
AGBL1
Target Full Name
Cytosolic carboxypeptidase 4
Target Function
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
Target Involvement
Corneal dystrophy, Fuchs endothelial, 8 (FECD8)
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
Peptidase M14 family
Target Tissue Specificity
Expressed in corneal endothelium.
Target Synonyms
AGBL1; CCP4; Cytosolic carboxypeptidase 4; EC 3.4.17.-; ATP/GTP-binding protein-like 1
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