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Recombinant Human DNA-directed RNA polymerases I, II, and III subunit RPABC4 (POLR2K)

ACP22811

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22811 Target NamePOLR2K
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-58Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP53803
Background Information
  • Uniprot Id

    P53803

  • Target Species

    Human

  • Target Name

    POLR2K

  • Target Full Name

    DNA-directed RNA polymerases I, II, and III subunit RPABC4

  • Target Function

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family

  • Target Synonyms

    POLR2K; DNA-directed RNA polymerases I; II; and III subunit RPABC4; RNA polymerases I; II; and III subunit ABC4; ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alpha

  • Target Background

    This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases.

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