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Recombinant Human Down syndrome cell adhesion molecule-like protein 1 (DSCAML1), Truncated

ACP14212

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14212 Target NameDSCAML1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TD84
Background Information
  • Uniprot Id

    Q8TD84

  • Target Species

    Human

  • Target Name

    DSCAML1

  • Target Full Name

    Cell adhesion molecule DSCAML1

  • Target Function

    Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells. Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.

  • Target Tissue Specificity

    Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.

  • Target Synonyms

    Down syndrome cell adhesion molecule 2; Down syndrome cell adhesion molecule like 1; Down syndrome cell adhesion molecule like protein 1; Down syndrome cell adhesion molecule-like protein 1; DSCAM2; DSCAML1; DSCL1_HUMAN

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