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| Cat.No | ACP14566 | Target Name | DRAXIN |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 26-349 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NBI3 |
|---|
Uniprot Id
Q8NBI3
Target Species
Human
Target Name
DRAXIN
Target Full Name
Draxin
Target Function
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Target Subcellular Location
Secreted.
Target Protein Families
Draxin family
Target Research Area
Neuroscience
Target Synonyms
AGPA3119; Chromosome 1 open reading frame 187 ; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; DRAXI_HUMAN; Draxin; FLJ34999; MGC117222; Neucrin; OTTHUMP00000002262; UNQ3119
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