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Recombinant Human Dynein heavy chain 1, axonemal (DNAH1), Truncated

ACP11126

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11126 Target NameDNAH1
Target SynonymsDNAH1; DHC7; DNAHC1; KIAA1410; Dynein heavy chain 1; axonemal; Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1; HSRF-1; hDHC7FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9P2D7
Background Information
  • Uniprot Id

    Q9P2D7

  • Target Species

    Human

  • Target Name

    DNAH1

  • Target Full Name

    Dynein axonemal heavy chain 1

  • Target Function

    Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme.

  • Target Involvement

    Spermatogenic failure 18 (SPGF18); Ciliary dyskinesia, primary, 37 (CILD37)

  • Target Subcellular Location

    Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.

  • Target Protein Families

    Dynein heavy chain family

  • Target Tissue Specificity

    Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain.

  • Target Synonyms

    DNAH1; DHC7; DNAHC1; KIAA1410; Dynein heavy chain 1; axonemal; Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1; HSRF-1; hDHC7

Inquire Recombinant Human Dynein heavy chain 1, axonemal (DNAH1), Truncated Now



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