Home Products Recombinant Human Extracellular serine/threonine protein kinase FAM20C (FAM20C)

Recombinant Human Extracellular serine/threonine protein kinase FAM20C (FAM20C)

ACP14980

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Specifications

Cat.No	ACP14980	Target Name	FAM20C
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	23-584	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IXL6

Background Information

Uniprot Id

Q8IXL6
Target Species

Human
Target Name

FAM20C
Target Full Name

Extracellular serine/threonine protein kinase FAM20C
Target Function

Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth. Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome. Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity. Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1. In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion.
Target Involvement

Raine syndrome (RNS)
Target Subcellular Location

Secreted. Golgi apparatus.
Target Protein Families

FAM20 family
Target Tissue Specificity

Widely expressed.
Target Research Area

Developmental Biology
Target Synonyms

C76981; Dentin matrix protein 4; DKFZp547C074; DMP-4; DMP4; DMP4_HUMAN; Extracellular serine/threonine protein kinase Fam20C; Fam20c; Family with sequence similarity 20 member C; GEF CK; Golgi enriched fraction casein kinase; Protein FAM20C; RNS

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Recombinant Human Extracellular serine/threonine protein kinase FAM20C (FAM20C)

Specifications

Immunogen Information

Inquire Recombinant Human Extracellular serine/threonine protein kinase FAM20C (FAM20C) Now

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